SGK1 upregulation in GFAP+ neurons in the frontal association cortex protects against neuronal apoptosis after spinal cord injury

Abstract Spinal cord injury (SCI) casts devastating and long-lasting impacts on the well-being of patients.Cognitive deficits and emotional disorders are common in individuals with SCI, yet the underlying mechanisms are not completely understood.Astrogliosis and glial scar formation occur during the subacute phase post-injury, playing complicated r

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Ten (not so) simple rules for clinical trial data-sharing.

Clinical trial data-sharing is seen as an imperative for research integrity and is becoming increasingly encouraged or even required by funders, journals, and other stakeholders.However, early experiences with data-sharing have been disappointing because they are not always conducted properly.Health data is indeed sensitive and not always easy to s

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Serotonergic stimulation induces nerve growth and promotes visual learning via posterior eye grafts in a vertebrate model of induced sensory plasticity

Sensory organs: drug induces nerve growth for opi the color that keeps on giving ectopic eye transplant A migraine drug that modulates neurotransmitter signaling can boost the neural connections of eyes grafted onto tadpoles to enhance vision.Michael Levin and colleagues from Tufts University in Medford, MA, USA, built on previous work from their l

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